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Faculty - Professors
Faculty > Professors > Donald W. Chakeres, M.D.


Donald W. Chakeres, MD   Donald W. Chakeres, MD
Professor; Section Chief, Neuroradiology
630 Means Hall
1654 Upham Dr
Ohio State University
Columbus, OH 43210
Phone: 614-293-8315
Fax: 614-293-6935
Donald.Chakeres@osumc.edu

 

C.V.

Primary Specialty:
Radiology-Neuroradiology

Clinical Interest:
Neuroradiology, high resolution MRI and CT, head and neck radiology

Research Interests:
High-resolution MRI of the Temporal Bone and Skull Base, High field safety and imaging, unification physic’s models

For many years I have focused on high resolution MRI of the temporal bone and other skull base structures. In collaboration with Dr. Petra Schmalbrock we have developed and implemented a number of advanced techniques for MRI at 1.5 T, many of which have since become standard techniques available on commercial units. We have documented the value of these techniques related to the clinical evaluation of patients with tumors and other skull base pathology.

Since 1999 I have worked on the development of ultra high field MRI at 8 and 7 T. I was the Director of the MRI Research Division at the OSU Medical School, Department of Radiology. We focused on achieving a better understanding of many of the critical fundamental issues that presently represent significant limitations to high field MR imaging. These limitations include: B1 field inhomogeneities, potential high SAR values, magnetic susceptibility artifacts, volume head coil configurations, and non-standard relaxometry techniques. My primary clinical focus was on high resolution imaging of the micro circulation of the brain, applications of phase imaging, and brain anatomic studies.

We completed extensive safety numerical simulations, phantom measurements and human studies. This data lead to the FDA revising the safety standard to include exposure to 8 T as a non significant risk device.

I have also developed an interest in unified physics theories since the late 1990s. The most recent work is based on a quantum model rooted in the most classic characteristics of quantum spectra and simple harmonic systems. The model is now quite robust and it is possible to derive the most fundamental constants as coupling constants to an accuracy of 9 digits exponentially starting with pi as the only known physical constant. This is possible if one understands the nature of the harmonic system. The abstract for the paper is printed below. The paper is available as a PDF file for a more detailed review.


Abstract: A Physics Unification Model: The neutron symphony

Pi can be derived as a dimensionless ratio from a mathematical formulation independent of any known physical value. The hypothesis is that the coupling constants between the fundamental physical constants analyzed as frequency equivalents in a unified spectrum represent an analogous situation where it is possible to derive them without any physical data if one understands the mathematical rules that restrict their possibilities. If there is only one set of possible values that fulfill all the rules of the relationships between fundamental constants simultaneously then it is possible to mathematically derive them. This paper demonstrates and explains this mathematical formulation. The main physical hypothesis is that the fundamental constants represent a unified quantum spectrum based on the annihilation frequency of the neutron from which all of the other values are derived. The mathematical formulation includes many classic physics elements including: logic, pi, but defined by the ratio of three physical values, dimensionless ratio coupling constants of two identical physical units (frequency equivalents), an infinite consecutive integer series, an infinite fractional consecutive integer series (quantum fractions), a singularity point, an Eigen function (exponential relationship), linear functions, complex numbers, and an inverse mathematical transformation (from a ratio of frequencies to quantum fraction exponent values plotted on a complex number plane). There are other elements that are not typical including: the fact that the linear functions are plotted on a complex number plane and represent exponents of ratios. Also the prime numbers are critical values that are associated with the harmonic lineage of associated physical entities (physically associated entities have common prime numbers products). The most unique mathematical restriction is that all of the complex number points and their associated intersecting lines must be defined by only three quantum linear distances on the complex number plane. From these three values only all of the others must related by the number of integer harmonic possibilities only including an infinite fractional integer series. The ratio of the three physical factors as frequencies that define these distances must also derive pi. The properties of hydrogen (ionization energy, Bohr radius, and mass of the electron) are the physical values related to pi and secondarily define the critical three complex number distances of this formulation.


download abstract as PDF: "The neutron symphony"